FGFR3 p.S249C
About
Gene context: FGFR3
Biomarker Type: Somatic Variant
Present: True
Chromosome: 4
Start Position: 1803568
End Position: 1803568
Reference Allele: C
Alternate Allele: G
Cdna Change: c.746C>G
Protein Change: p.S249C
Variant Annotation: Missense
Exon: 6
Rsid: rs121913483
Hgvsg: 4:g.1803568C>G
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.
| Organization(s) | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| EMA (1) FDA (1) HSE (1) | FGFR3 p.S249C | Bladder Urothelial Carcinoma | Erdafitinib |