CHEK1

About

Location: 11q24.2

Mappings

HGNC: HGNC:1925

Ensembl: NM_001114122.3

NCBI: ENSG00000149554

Refseq: 1111

Biomarkers

CHEK1 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
CHEK1 pathogenic variants Germline Variant 1 1
CHEK1 oncogenic variants Somatic Variant 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
FDA (1) CHEK1 pathogenic variants Prostate Adenocarcinoma Olaparib
FDA (1) CHEK1 oncogenic variants Prostate Adenocarcinoma Olaparib