CHEK2

Biomarkers

CHEK2 is involved in the following curated biomarkers.

Name	Biomarker type	Propositions	Statements
CHEK2 pathogenic variants	Germline Variant	2	2
CHEK2 oncogenic variants	Somatic Variant	2	2

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organization(s)	Biomarker(s)	Cancer type	Therapy(ies)
FDA (1)	CHEK2 pathogenic variants	Prostate Adenocarcinoma	Olaparib
FDA (1)	CHEK2 pathogenic variants	Prostate Adenocarcinoma	Enzalutamide, Talazoparib
FDA (1)	CHEK2 oncogenic variants	Prostate Adenocarcinoma	Olaparib
FDA (1)	CHEK2 oncogenic variants	Prostate Adenocarcinoma	Enzalutamide, Talazoparib