MRE11

About

Location: 11q21

Mappings

HGNC: HGNC:7230

Ensembl: ENSG00000020922

NCBI: 4361

Refseq: NM_005591.4

Biomarkers

MRE11 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
MRE11 oncogenic variants Somatic Variant 1 1
MRE11 pathogenic variants Germline Variant 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) MRE11 oncogenic variants Prostate Adenocarcinoma Enzalutamide, Talazoparib
Sensitivity (+) MRE11 pathogenic variants Prostate Adenocarcinoma Enzalutamide, Talazoparib