MRE11

About

Location: 11q21

Mappings

HGNC: HGNC:7230

Ensembl: ENSG00000020922

NCBI: 4361

Refseq: NM_005591.4

Biomarkers

MRE11 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
MRE11 oncogenic variants Somatic Variant 1 1
MRE11 pathogenic variants Germline Variant 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
FDA (1) MRE11 oncogenic variants Prostate Adenocarcinoma Enzalutamide, Talazoparib
FDA (1) MRE11 pathogenic variants Prostate Adenocarcinoma Enzalutamide, Talazoparib