Regulatory approval

Published by the Health Service Executive.

The Republic of Ireland's Health Service Executive (HSE) has approved paclitaxel (80) in combination with trastuzumab therapy - 7 day (12 weeks) for reimbursement as a treatment option for the adjuvant treatment of HER2 positive, node-negative breast cancer of tumor size <= 3 cm.

This is written in the approval document as:

Adjuvant Treatment of HER2 positive, Node-Negative Breast Cancer of tumour size <= 3cm.

Citation

PACLitaxel (80) and Trastuzumab Therapy - 7 day (12 weeks), 2022, version number 4, NCCP National SACT Regimen, NCCP, viewed 21/07/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/breast/512-paclitaxel-80-and-trastuzumab-therapy-%E2%80%93-7-day-12-weeks-.pdf

Therapeutic response

Precision oncology relationships for therapeutic response derived from this regulatory approval.

Type	Biomarker(s)	Cancer type	Therapy(ies)
Sensitivity (+)	HER2-positive	Invasive Breast Carcinoma	Paclitaxel, Trastuzumab