Therapeutic Response

v::ROS1 status confers therapeutic sensitivity to Crizotinib in patients with Non-Small Cell Lung Cancer.

Statements

Source and description
Xalkori (crizotinib) [product information]. EMA. The European Medicines Agency (EMA) has authorized crizotinib for the treatment of adult patients with ROS1-positive advanced non-small cell lung cancer (NSCLC).
Xalkori (crizotinib) [package insert]. FDA. The U.S. Food and Drug Administration granted approval to crizotinib for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK) or ROS1-positive, as detected by an FDA-approved test.