Therapeutic Response

PD-L1 (CPS) >= 1 status confers therapeutic sensitivity to Paclitaxel in combination with Pembrolizumab in patients with High-Grade Serous Fallopian Tube Cancer.

Statements

Source and description

Keytruda (pembrolizumab) [package insert]. FDA. The U.S. Food and Drug Administration granted approval to pembrolizumab in combination with paclitaxel, with or without bevacizumab, for the treatment of adult patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal carcinoma whose tumors express PD-L1 (CPS >= 1) as determined by an FDA-authorized test, and who have received one or two prior systemic treatment regimens.