Molecular Oncology Almanac
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Therapeutic Response

PD-L1 (CPS) >= 1 status confers therapeutic sensitivity to Bevacizumab in combination with Paclitaxel and Pembrolizumab in patients with Peritoneal Serous Carcinoma.

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Statements

Source and description
Keytruda (pembrolizumab) [package insert]. FDA.

The U.S. Food and Drug Administration granted approval to pembrolizumab in combination with paclitaxel, with or without bevacizumab, for the treatment of adult patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal carcinoma whose tumors express PD-L1 (CPS >= 1) as determined by an FDA-authorized test, and who have received one or two prior systemic treatment regimens.

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