Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that BRAF p.V600K status confers therapeutic sensitivity to Vemurafenib in patients with Melanoma.

This statement is based on a regulatory approval from the Health Service Executive:

Treatment of adult patients with BRAF V600 mutation-positive unresectable or metastatic melanoma.

Citation

Vemurafenib Monotherapy, 2020, version number 5, NCCP National SACT Regimen, NCCP, viewed 18/01/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/melanoma/102-vemurafenib-monotherapy-regimen.pdf