Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that Wild type ALK, Wild type EGFR status confers therapeutic sensitivity to Carboplatin, Ipilimumab, Nivolumab, Paclitaxel in patients with Non-Small Cell Lung Cancer.

This statement is based on a regulatory approval from the Health Service Executive:

First-line treatment of metastatic squamous non-small cell lung cancer (NSCLC) in adults whose tumours have no sensitising EGFR mutation or ALK translocation.

Citation

Nivolumab, ipilimumab, CARBOplatin and PACLitaxel Therapy, 2023, version number 2, NCCP National SACT Regimen, NCCP, viewed 04/04/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/lung/712.pdf