Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that v::RET status confers therapeutic sensitivity to Vandetanib in patients with Medullary Thyroid Cancer.

This statement is based on a regulatory approval from the Health Service Executive:

Treatment of medullary thyroid cancer (MTC) in patients with Rearranged during Transfection (RET) mutation positive, unresectable locally advanced or metastatic disease.

Citation

Vandetanib Therapy, 2023, version number 5, NCCP National SACT Regimen, NCCP, viewed 01/09/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/headandneck/242vandetanibmonotherapy.pdf