Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that HER2-negative, PR positive status confers therapeutic sensitivity to Abemaciclib, Anastrozole in patients with Invasive Breast Carcinoma.

This statement is based on a regulatory approval from the Health Service Executive:

Abemaciclib in combination with endocrine therapy for the adjuvant treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-positive early breast cancer at high risk of recurrence.

Citation

Abemaciclib Therapy, 2024, version number 1, NCCP National SACT Regimen, NCCP, viewed 21/07/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/breast/619-abemaciclib-therapy.pdf