H3-3A p.K27M
About
Gene context: H3-3A
Biomarker Type: Somatic Variant
Present: True
Chromosome: 1
Start Position: 226252135
End Position: 226252135
Reference Allele: A
Alternate Allele: T
Cdna Change: c.83A>T
Protein Change: p.K28M
Variant Annotation: Missense
Exon: 2/4
Rsid: rs1057519903
Hgvsg: 1:g.226252135A>T
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.
Type | Biomarker(s) | Cancer type | Therapy(ies) | |
---|---|---|---|---|
Sensitivity (+) | H3-3A p.K27M | Diffuse Midline Glioma | Dordaviprone |