FGFR2

Biomarkers

FGFR2 is involved in the following curated biomarkers.

Name	Biomarker type	Propositions	Statements
FGFR2 rearrangements	Rearrangement	3	4
FGFR2::v	Rearrangement	4	6
FGFR2::BICC1	Rearrangement	1	2
FGFR2::CASP7	Rearrangement	1	2

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Type	Biomarker(s)	Cancer type	Therapy(ies)
Sensitivity (+)	FGFR2::BICC1	Bladder Urothelial Carcinoma	Erdafitinib
Sensitivity (+)	FGFR2::CASP7	Bladder Urothelial Carcinoma	Erdafitinib
Sensitivity (+)	FGFR2::v	Intrahepatic Cholangiocarcinoma	Elacestrant
Sensitivity (+)	FGFR2 rearrangements	Intrahepatic Cholangiocarcinoma	Elacestrant
Sensitivity (+)	FGFR2::v	Cholangiocarcinoma	Pemigatinib
Sensitivity (+)	FGFR2 rearrangements	Cholangiocarcinoma	Pemigatinib
Sensitivity (+)	FGFR2::BICC1	Bladder Urothelial Carcinoma	Erdafitinib
Sensitivity (+)	FGFR2::CASP7	Bladder Urothelial Carcinoma	Erdafitinib
Sensitivity (+)	FGFR2::v	Intrahepatic Cholangiocarcinoma	Futibatinib
Sensitivity (+)	FGFR2::v	Intrahepatic Cholangiocarcinoma	Futibatinib
Sensitivity (+)	FGFR2 rearrangements	Intrahepatic Cholangiocarcinoma	Futibatinib
Sensitivity (+)	FGFR2::v	Cholangiocarcinoma	Infigratinib
Sensitivity (+)	FGFR2::v	Intrahepatic Cholangiocarcinoma	Elacestrant
Sensitivity (+)	FGFR2 rearrangements	Intrahepatic Cholangiocarcinoma	Elacestrant