HRAS

About

Location: 11p15.5

Mappings

HGNC: HGNC:5173

Ensembl: NM_005343.4

NCBI: ENSG00000174775

Refseq: 3265

Biomarkers

HRAS is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
Wild type HRAS Wild type 5 5

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
FDA (1) Wild type HRAS, Wild type KRAS Colorectal Adenocarcinoma Fluorouracil, Oxaliplatin, Panitumumab
FDA (1) Wild type HRAS, Wild type KRAS Colorectal Adenocarcinoma Panitumumab
EMA (1) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab
EMA (1) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab, Irinotecan
EMA (1) EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS Colorectal Adenocarcinoma Cetuximab, Fluorouracil, Oxaliplatin