PDGFRA
About
Location: 4q12
Mappings
Biomarkers
PDGFRA is involved in the following curated biomarkers.
| Name | Biomarker type | Propositions | Statements |
|---|---|---|---|
| FIP1L1::PDGFRA | Rearrangement | 2 | 3 |
| PDGFRA rearrangements | Rearrangement | 2 | 3 |
| PDGFRA p.D842V | Somatic Variant | 1 | 2 |
Therapeutic response
Precision oncology relationships for therapeutic response involving this gene.
| Organization(s) | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| EMA (1) FDA (1) | FIP1L1::PDGFRA | Chronic Eosinophilic Leukemia, NOS | Imatinib | |
| FDA (1) | FIP1L1::PDGFRA | Gastrointestinal Stromal Tumor | Imatinib | |
| EMA (1) FDA (1) | PDGFRA rearrangements | Myelodysplastic Syndromes | Imatinib | |
| EMA (1) | PDGFRA rearrangements | Myeloproliferative Neoplasm | Imatinib | |
| EMA (1) FDA (1) | PDGFRA p.D842V | Gastrointestinal Stromal Tumor | Avapritinib |