Molecular Oncology Almanac
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Therapeutic Response

ABL1 p.T315I and BCR::ABL1 status confers therapeutic sensitivity to Asciminib in patients with Chronic Myelogenous Leukemia.

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Statements

Source and description
Scemblix (asciminib) [package insert]. FDA.

The U.S. Food and Drug Administration granted approval to asciminib for the treatment of adult patients with philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP) with the T315I mutation.

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