Molecular Oncology Almanac
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Therapeutic Response

EGFR Exon 19 (Deletion) status confers therapeutic sensitivity to Erlotinib in combination with Ramucirumab in patients with Non-Small Cell Lung Cancer.

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Statements

Source and description
Cyramza (ramucirumab) [package insert]. FDA.

The U.S. Food and Drug Administration granted approval to ramucirumab in combination with erlotinib for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) mutations.

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