EGFR Exon 19 (Deletion)

About

Gene context: EGFR

Biomarker Type: Somatic Variant

Present: True

Chromosome: 7

Variant Annotation: Deletion

Exon: 19

Requires Oncogenic: True


Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
View API

Therapeutic response

Precision oncology relationships for therapeutic response involving this biomarker.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Dacomitinib
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Erlotinib
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Gefitinib
EMA (2) FDA (3) HSE (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Osimertinib
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Carboplatin, Osimertinib, Pemetrexed
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Cisplatin, Osimertinib, Pemetrexed
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Erlotinib, Ramucirumab
EMA (3) FDA (2) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Amivantamab, Lazertinib
EMA (1) FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Amivantamab, Carboplatin, Pemetrexed
EMA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Bevacizumab, Erlotinib
EMA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Cisplatin, Osimertinib
EMA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Carboplatin, Osimertinib
FDA (1) EGFR Exon 19 (Deletion) Non-Small Cell Lung Cancer Datopotamab deruxtecan