Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that BRAF p.V600E status confers therapeutic sensitivity to Dabrafenib in patients with Melanoma.

This statement is based on a regulatory approval from the Health Service Executive:

Treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.

Citation

Dabrafenib Monotherapy, 2021, version number 5, NCCP National SACT Regimen, NCCP, viewed 08/01/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/melanoma/237dabrafenib.pdf