Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that HER2-positive status confers therapeutic sensitivity to Carboplatin, Docetaxel, Pertuzumab, Trastuzumab in patients with Invasive Breast Carcinoma.

This statement is based on a regulatory approval from the Health Service Executive:

Neoadjuvant treatment of adult patients with HER2-positive locally advanced, inflammatory or early breast cancer at high risk of recurrence.

Citation

DOCEtaxel, CARBOplatin, Trastuzumab and Pertuzumab (TCHP) Therapy, 2023, version number 2, NCCP National SACT Regimen, NCCP, viewed 15/04/2024, https://www.hse.ie/eng/services/list/5/cancer/profinfo/chemoprotocols/breast/722-docetaxel-carboplatin-trastuzumab-and-pertuzumab-tchp-therapy.pdf