Lapatinib

About

Therapy type: Targeted therapy

Therapy strategy: HER2 inhibition

Mappings

NCI Thesaurus: Lapatinib (ncit:C26653)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this therapy.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) HER2-positive Invasive Breast Carcinoma Capecitabine, Lapatinib
Sensitivity (+) ER positive, HER2-positive Invasive Breast Carcinoma Lapatinib, Letrozole
Sensitivity (+) HER2-positive, PR positive Invasive Breast Carcinoma Lapatinib, Letrozole
Sensitivity (+) ER positive, HER2-positive, PR positive Invasive Breast Carcinoma Lapatinib, Letrozole
Sensitivity (+) HER2-positive Invasive Breast Carcinoma Capecitabine, Lapatinib
Sensitivity (+) ERBB2 amplification Invasive Breast Carcinoma Capecitabine, Lapatinib
Sensitivity (+) ER positive, HER2-positive, PR negative Invasive Breast Carcinoma Lapatinib, Trastuzumab
Sensitivity (+) ER positive, ERBB2 amplification, PR negative Invasive Breast Carcinoma Lapatinib, Trastuzumab
Sensitivity (+) ER positive, HER2-positive, PR positive Invasive Breast Carcinoma Lapatinib, Letrozole
Sensitivity (+) ER positive, ERBB2 amplification, PR positive Invasive Breast Carcinoma Lapatinib, Letrozole
Sensitivity (+) HER2-positive Invasive Breast Carcinoma Capecitabine, Lapatinib