FLT3-ITD

About

Gene context: FLT3

Biomarker Type: Somatic Variant

Present: True

Chromosome: 13

Variant Annotation: Internal Tandem Duplication (ITD)

Requires Oncogenic: True


Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
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Therapeutic response

Precision oncology relationships for therapeutic response involving this biomarker.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Midostaurin
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Gilteritinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Gilteritinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Idarubicin, Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Midostaurin
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Idarubicin, Quizartinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Midostaurin
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Midostaurin
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Midostaurin
Sensitivity (+) FLT3-ITD Acute Lymphoid Leukemia Gilteritinib
Sensitivity (+) FLT3-ITD Acute Myeloid Leukemia Cytarabine, Daunorubicin, Quizartinib